Delirium – Gold Standard Nonpharmacologic Treatment Checklist
Pearl: These nonpharmacologic interventions are the gold standard to delirium care in the hospital and have been found to prevent delirium by 30-40%! (Postoperative delirium in older adults: best practice statement from the American Geriatrics Society)
Address underlying medical issues
Treat the precipitant(s) of delirium
Assess and treat pain
- Consider acetaminophen 1g TID (or 650 mg TID if cirrhosis) as pain is often underreported
- Consider low dose opioid, if necessary
Enhance hydration and nutrition
- Consider nutrition consult
- If there is underlying dementia, consider a speech therapy consult for education on optimal ways to present meals
Avoid constipation and urinary retention
- Consider scheduling a bowel regimen (avoid docusate monotherapy)
- Consider a bladder scan
Review for deliriogenic medications and adjust appropriately
Pay particular attention to anticholinergics, sedatives, and muscle relaxants (which often have high anticholinergic burden)
Review for deliriogenic medications
Reorient frequently and provide reassurance
Encourage family at the bedside or the presence of a patient care attendant who can provide simple communications to prevent escalation of behavior
- Provide family education using an informational handout
Consider occupational or speech therapy consult to assist with reorientation strategies
Keep white board updated
Ensure glasses, hearing aids/PocketTalkers are present, if needed
Maintain safe mobility
Remove nonessential tethers
- Foley catheter, physical restraints (AGS Choosing Wisely), IVs , cardiac monitoring, etc
Mobilize at least 2-3x per day
Consult physical and occupational therapy early in hospital course
Optimize sleep
Keep lights on and keep active during the day
- Avoid napping
- Consider cognitive stimulation as tailored to patient interests and abilities. Consider “Care Square”, chaplain visits, music/pet therapy, etc
- Consider physical activity and frequent daytime mobilization
Reduce nighttime interruptions
- Consider limiting labs and vitals overnight (such as 11 pm to 5 am)
If needed, can consider melatonin 3 mg qhs or the judicious use of trazodone
What about the Intensive Care Unit?
While the above recommendations are generally for floor patients, the ICU’s ABCDEF bundle (see SCCM information here) incorporates many of these elements and is associated with decreased risk of delirium (OR = 0.60; CI 0.49-0.72), hospital death within 7 days, physical restraint use, and discharge to facility other than home.
- Assess, prevent, and manage pain
- Both spontaneous awakening trials (SAT) and Spontaneous Breathing Trials (SBT)
- Choice of analgesia and sedation
- Delirium: Assess, prevent, and manage
- Early mobility and exercise
- Family engagement and empowerment